Ana Silva

Ana Silva
Ana Silva

Position: Research Associate

Department: CITIID / Department of Medicine

Keywords: molecular biology, DNA repair, replication, virology, SARS-CoV-2

I am a molecular biologist working in Paul Lehner’s lab at the Cambridge Institute for Therapeutic Immunology & Infectious Disease (CITIID), since March 2018.

So far, I have had an exciting and international scientific career. I did my undergrad in Biomedical Sciences – Molecular Biomedicine at the University of Aveiro in Portugal, followed by a master’s degree in Forensic Genetics at the University of Porto. Afterwards, I moved to France to do my PhD at the Institut Curie, where I studied how the Homologous Recombination maintains genome stability during DNA replication. In 2018, I started my current position at the University of Cambridge.

My research has been very diverse, and I have had the privilege of working on many interesting topics. When I first started working in Paul Lehner’s lab my research focused on chromatin biology / epigenetics applied to retrotransposons, viruses, and extra-chromosomal DNA. Since the COVID-19 crisis, I have extended my research interests and began working on a collaborative project to better understand how the Spike protein of SARS-CoV2 interacts with cell surface proteins. By characterising these interactions, we’ll have a clearer picture of why the virus affects certain tissues more than others and why there is a huge variation in symptoms.

Get in touch: acc80 [at] cam.ac.uk